Demand CS is not supposed to be sprayed directly on clothes. If the clothes have been sprayed, I would recommend to wash them with soap and water. If the closet was simply treated - baseboards, etc, then there is usually no need to wash the clothes. Demand CS can be a skin irritant, but in most cases is the product of choice indoors because of its low mixing rate, almost odorless and colorless appearance. Its a great product.